End Senseless Horse Abuse and Cruelty


Target: Chief Executive Officer of Pfizer, Ian C. Read

Goal: Stop the use of horse urine in hormone medication and the abuse of pregnant horses necessary for extraction.

Conjugated equine estrogen, known as CEE, is a chemical found in the urine of pregnant horses that is used in Pfizer’s drugs for menopause and osteoporosis, and it requires mares to be repeatedly pregnant for up to 12 years at a time. Pfizer makes more than $1 billion per year off the use of CEE and have no intention on stopping its use despite the pain it inflicts on horses and the health threat it poses to humans. Demand Pfizer end its use of CEE and protect the health and well-being of animals as well as consumers.

During the process it takes to acquire CEE, mares spend six months out of their 11-month long repeated pregnancies in stalls that are too small for them to comfortably turn around or even lie down. They spend the majority of their time standing on cold concrete floors with bulky urine bags between their back legs that cause infections and severely limit their movement. The foals and infertile mares are often sold to “kill buyers” and brought to slaughter.

What’s more, instead of bringing help and healing, drugs containing CEE are not well tolerated by humans and can lead to cancer and cardiovascular issues.

Sign the petition below to let Pfizer know that you will not use, purchase, or recommend any of the company’s products until this cruel and unnecessary treatment of horses comes to an end.


Dear Mr. Read,

Menopause and osteoporosis are serious ailments, and many people rely on the medications you provide to help and heal them. But right now, your medication is only causing more damage than good. Medications such as Premarin, Prempro, and Duavee are produced with CEE, also known as conjugated equine estrogen, and are hurting both your customers and your work animals. CEE has been directly linked to cancer and has caused cardiovascular issues in others, at the expense of your mares that are repeatedly pregnant for 12 years at a time in uncomfortable and unhealthy conditions.

I urge you to stop using CEE to create your products. It is harmful to the consumer, and harmful to your work animals. There are almost always risks when taking hormone medications, but there are countless alternatives that do not risk cancer or other permanent, even deadly, effects. I refuse to allow myself or anyone I know to come to harm or indirectly support the harm of an innocent animal by using your products. I will continue to boycott your inhumane, potentially life-threatening products until Pfizer adjusts its production methods accordingly.


[Your Name Here]

Photo credit: Karolina Grabowska

Sign the Petition

  • Only your name will be displayed. You can edit your auto-fill information here. By signing, you accept our terms and may receive updates on this and related causes.
FacebookCare2 NewsTwitterEmailShare


  1. Bina Pannell says:

    Is no animal scared to these pharma companies? They do not belong to research labs to do what they want with/to them.

    Who was the idiot who came up with the idea of experimenting on animals in the first place? I hope he’s burning in hell!

    • It was mainly Rene´Descartes, the infamous vivisectioner from the 1500s….if you can believe we’re STILL stupidly following such outdated precepts! Descartes should have been burned at the stake for what he did to animals, and for purporting they were akin to mechanical “clocks” – no feelings, no consciousness, no nothin’. Yet his insane viewpoint has been taken up and conveniently followed ever since. That bastard set the tone for all that’s followed, as to how other living species are viewed and treated. The human race is dumber than posts, and more insensitive than any other.

  2. Kathy Williams says:

    KIRBY: I signed your petition, but please correct the second sentence in the last paragraph, i.e. “…harmful to your work animals.”

    And regarding the issue: Wow. It boggles my mind to think that drugs like Premarin are STILL prescribed in this day and age. But why should this surprise me? Dairy farmers do essentially the same thing to cows.

    And Pfizer – just like virtually every other big corporation – stubbornly refuses to join the rest of us in the 21st century. Considering the amount of unnecessary torture they inflict on millions of sentient beings- most of them not even recognized by the albeit weak ‘protection’ of the AWA – I seriously doubt that any petition will make a difference. ALL so-called scientists have had decades to implement the Three Rs of Research. But instead of reducing the number of animals used in experiments, the number is rapidly increasing thanks to genetic modification.

  3. Heather Brophy says:


  4. There are enough alternative – and far more reliable – research methods nowadays : please leave out vivisection entirely, including that ghastly horse breeding program of yours. Not only are horses in no way biologically similar to humans but they possibly have more sense as well (even if it oughtn’t take much…) – The need for budget cuts is often evoked by the pharma industry : quite farcical in itself, the industry being one of the richest in existence!

  5. Sam Outhorn says:

    Horse have a touch of the divine in them; they are perfect in themselves, very beautiful. Isn’t admiring and caring for them enough? Or are corporations so indifferent to needless suffering and tormenting they prefer to ignore the beauty? The “urine of pregnant mares ” bit, in the news for decades, is downright obnoxious besides being dangerous and totally useless. Why not stick to human urine if you must: seems far more plausible, somehow…

  6. Lesley Parker says:

    I signed the petition, but please correct part of the first line, in which you state that menopause is a ‘serious ailment’ – it is a natural part of the ageing process. Other than that, I fully support the petition. I have seen reports from equine rescue centres that have managed to take over the care of some of these poor mares, and it does not make pretty reading, and it seems that very shortly after each mare foals, her foal is taken away, killed, and the whole process starts again. It is a miserable life for mares, and there is no plausible excuse for keeping them in these conditions. Let’s bring this to the notice of as many people as possible.

  7. “So many people insist they are against animal abuse, cruelty, suffering and the inhumane treatment of animals, yet they don’t understand they are actively engaging in and supporting egregious suffering, abuse, cruelty and inhumane treatment when they eat animals and their ‘by-products.’ If you are against cruelty, suffering and inhumane treatment, then you go vegan. It’s just that simple.” – Sarah Kiser

  8. It is simply unbelievable to me that even DECADES after the horrors behind Premarin were exposed, there are STILL masses of women out there who are utterly CLUELESS about what Big Pharma does to get horse urine…AND what a “junk science” and harmful premise the whole idea is to begin with! How dumb IS everybody anyway?!?! Women of the western world, JUST GET A BRAIN CELL AND REFUSE to take these unnatural, dangerous, and animal-torturing substances at all!!! Instead, educate yourselves about bio-identical hormone replacement therapy and other safer methods, that won’t hurt you OR other animals! QUIT FUNDING BIG PHARMA’s evils!!!!!!

Leave a Reply

Your email address will not be published. Required fields are marked *


Facebook Comments


6870 Signatures

  • Yaedi Ignatow
  • Joy Martin
  • Maria Smithton
  • jenny morgan
  • Kim Whitehead
  • Gertie Hunt
  • Pam Treeby
  • Chrissie jacques
  • Danie Crouch
1 of 687123...687
Skip to toolbar